Pharmacokinetic studies can become a bottleneck in the screening phase due to the high number of samples collected to assess the PK properties of multiple molecules, in various time points, and by alternative administration routes. Cassette dosing, simultaneous administration of multiple molecules in one animal, dramatically reduces the number of samples collected and animals sacrificed, and consequently, saves time and money. Read more on our PK expertise from this link.
In December 2011 we offer SimaPilot -a cassette dosing study:
* Up to 5 simultaneously administered molecules
* In rat or in mouse
* With 5 time points, 2 animals per time point
* With iv and po administration
* The parent concentrations are analysed by UPLC/MS-MS
During the campaign, the price of the SimaPilot includes free Plasma Protein Binding (RED) for the same molecules in rat or mouse.
This offer is valid until the end of 2011. The studies will be conducted in January – February, 2012. Maximum of one cassette of compounds per a customer.