ADME/DMPK for lead optmization

ADME/DMPK services

• Computational logP, logD, logS, pKA and BBB predictions
• Experimental logP, logD, logS and pKA analysis
• Plasma protein binding
• Metabolite identification and stability
• CYP identification, inhibition and induction
• PAMPA, Caco-2 and skin permeabilityn

Related services

• Computational bioactivity and toxicology prediciton
• Virtual HTS, ligand, target, and reverse docking
• Library design
• Scaffold hopping and optimization
• In vivo disease models
• Toxicity and safety models
• Regulatory guidance and consulting
• Biomarker discovery and validation

ADME/DMPK services

• Computational logP, logD, logS, pKA and BBB predictions
• Experimental logP, logD, logS and pKA analysis
• Plasma protein binding
• In vitro metabolism
• CYP identification, inhibition and induction
• PAMPA, Caco-2 and skin permeabilityn

All our studies are tailored on customer’s request. We also offer development a novel disease models, including the analytics capabilities in SBW, including genomics, proteomics, live imaging, gross and histopathology.


Follow this link to retrive a comprehensive list of our ADME/DMPK models.