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SBW News
- Our participation in R&D projects for new in vivo methods and models: diabetes, obesity, cancer, PK and BBB
- SBW publication supporting Animal wellfare- 3´R principles
- Three long-term phase III oncology studies analysed by SBW/4Pharma
- Meet us in Bio International Convention, May 3-6, 2010 in Chicago, IL
- SBW is recruiting
- Early alert: In vitro genotoxicty studies to become available in March
- SBW strong also in proteomics services
- SBW Roadshow in Medicon Valley
- SBW Roadshow in Stockholm area and Uppsala
- Large customers reward in Feb-May'10 get an amzaing Apple iPAD !
Pain models
Related services
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Persistent painThe formalin induced persistent pain model is based on formalin caused tissue injury. It is used to assess the analgesic efficacy of the new compounds in pain with tissue damage. Thermal pain reflexThe thermal pain reflex model measures the efficacy of the new compound to alleviate the pain induced by footpad being in contact with a heated surface. The latency time of the first hind paw response is measured in mice or rats. Acetic acid induced writhingThe Acetic Acid induced writhing is a very good model to evaluate the analgesic or antinociceptive effect or activity of a drug molecule in mice or rats. Before inducing the writhing, animals are dosed with the reference compound or the test compound. The writhing is induced by intraperitoneal injection acetic acid in distilled water. Tail flick latency modelThe tail flick latency test is animal model of acute pain test in mice or rats. The pre-‐treatment latency of tail flick response (initial reaction time) is noted down for each animal. The analgesic effect of the test drug can be evaluated by increase in the tail flick latency period. Other in vivo models of pain areaIn addition to the models described above, we also provide the following pain related models
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Please follow this link to retrieve a detailed fact sheet of the Persistent pain model