SBW is an integrated CRO that offers comprehensive world class services, expertise and platforms for drug discovery as well as for functional food and chemical safety industries. Read more about SBW>>
Biomarkers and Discovery Biology
We use our expertise in protein analysis and proteomics for discover and verify new biomarkers, deconvolute the targets of small molecues discovered in phenotypic screens and study protein-ligand interactions. We work on nanoLC-MS/MS, protein and antibody arrays, BiaCORE and other platforms. We also provide the expertise needed in bioinformatics.
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Biomarker discovery and verification
In vitro assay design
Proteomics, protein interactions and target deconvolution |
Bioanalytics and ADME
We conduct both in vitro and in vivo studies in ADME/DMPK areas (rodents and non-rodent species) as well as in silico methods. Our special expertise is in metabolism, including metabolite identification, characterisation of reactive metabolites and drug interaction analysis. We provide also expertise to design the lead optimization studies for drug discovery projects.
Bioanalytics and ADME
Metabolism and reactive metabolites
Pharmacokinetics and bioanalytics
Permeability, plasma and tissue protein binding, physicochemical analysis, in silico predictions |
Disease models
Our expertise is in selected preclinical disease models. We combine in-life phase, non-invasive in vivo imaging and body composition analysis as well as telemetry in addition to hematology, clinical chemistry, biochemistry and histology analysis.
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Type I and II diabetes and obesity
Coronay-heart, hypertension and stroke
Oncology
Gastro-intestinal |
Toxicology and safety
We provide you with a unique 360-degree approach to toxicology. We are able to serve in silico, in vitro and in vivo toxicology. For in silico toxicology we have our own Ontomine expert system and for exprimetnal toxicology, we work both in early non-GLP and as well regulatory GLP toxicology areas.
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Early non-GLP and regulatory GLP toxicology
Ontomine in silico toxicity predictions
Eurotox toxicology consultation for regulatory preclinical studies |
Functional food industries
The health claims of functional foods and food ingredients, especially with novel food ingredients and nutraceuticals require solid scientific proof of efficacy and safety. We provide the expertise in efficacy testing, in areas like hypertension, coronary-heart diseases, diabetes and obesity as well as in toxicological testing.
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Efficacy testing
Safety testing
Regulatory consultation |
REACH chemical safety
As needed for the registration of chemicals to the ECHA authorities, we provide the expertise both in the GLP toxicology testing as well as in consultancy for the safety testing aspects and strategies. We help you both to understand what exact toxicological tests are needed as well as conduct them.
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Regulatory GLP toxicology
Eurotox toxicology consultation for regulatory toxicology studies |
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A major part of our activities is to help our customers to choose the right tests for their projects, interpret the results and aid in managing their projects with the help of our wide expertise in drug discovery and development, REACH and functional food industries. We call this Scientific Account Management.
Majority of our studies are tailored on customer’s request. We also offer development a novel disease models, including the analytics capabilities in SBW, including proteomics, hematology, clinical chemistry, biochemistry, non-invasive live imaging, gross and histopathology.
Follow this link to retrive a brochure of SBW platforms and business models.
Partnership in drug discovery and development
SBW provides a comprehensive spectrum of knowledge, expertise and instrumentation for various stages in drug discovery and development. We can offer for our customers comprehensive solutions, tailored for each project, where the parts of SBW platforms are utilized together with the customer’s own expertise.
This mixed-model ensures efficient progress in drug research, where the customer has constantly access to the whole portfolio of SBW knowledge.
Please follow this link to retrieve a general brochure of SBW.
